Products By Therapeutical Index
Alimentary System
-
Gastro-Intestinal Infections; Diarrhea
&
Ear , Nose & Oropharynx
-
Oropharyngeal Preparations
&
Genito-Urinary System
-
Reactants on Vagina,Urethra
&
Infections
-
Antibiotics
Antitrichomonal
Indications
Trichomoniasis
Symptomatic Trichomoniasis
Metrozole is indicated for the treatment of symptomatic trichomoniasis in women and men, when the presence of the trichomonad has been confirmed by appropriate laboratory procedures.
Asymptomatic Trichomoniasis
Metrozole is indicated in the treatment of asymptomatic women, when the organism is associated with endocervicitis, cervicitis or cervical erosion.
Asymptomatic Consorts
Trichomoniasis vaginalis infection is a venereal disease. Therefore, asymptomatic sexual partners of treated patients should be treated simultaneously if the organism has been found to be present, in order to prevent reinfection of the partner. During the treatment, it is recommended that the patient refrain from sexual intercourse, or the male partner use a condom to avoid reinfection.
Amebiasis
Metrozole is indicated in the treatment of acute intestinal amebiasis (amebic dysentery) and amebic liver abscess.
Composition
Metrozole Suspension
Each teaspoonful (5 ml) contains Metronidazole (as benzoyl) 125 mg
Metrozole 250 Tablets
Each tablet contains Metronidazole 250 mg.
Metrozole 500 Tablets
Each tablet contains Metronidazole 500 mg.
Action
Metronidaole is an antiprotozoal agent; anaerobic antibacterial agent.
Metrozole is active against a wide range of pathogenic microorganisms notably species of Bacteroides, Fusobacteria, Clostridia, Eubacteria, anaerobic cocci and Gardnerella vaginalis. It is also active against Trichomonas, Entamoeba histolytica, Giardia lamblia and Balantidium coli.
It is suggested that unchanged metronidazole penetrates the protozoan cell, where the nitro group is reduced to a hydroxyl or amine group that reacts with DNA and stops nucleic acid synthesis.
